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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
26.67
Human Site:
Y315
Identified Species:
41.9
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Chimpanzee
Pan troglodytes
XP_523815
451
50966
R272
L
M
R
S
G
H
N
R
A
V
D
W
W
S
L
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Dog
Lupus familis
XP_537702
525
59107
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Rat
Rattus norvegicus
P67999
525
59113
Y315
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
Y272
C
K
L
N
L
P
P
Y
L
T
Q
E
A
R
D
Chicken
Gallus gallus
P18652
752
84421
F302
A
K
L
G
M
P
Q
F
L
S
A
E
A
Q
S
Frog
Xenopus laevis
P10666
629
71268
F284
A
K
L
G
M
P
Q
F
L
S
N
E
A
Q
S
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F289
A
K
L
G
M
P
Q
F
L
S
L
E
A
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
M489
R
I
Q
K
E
Q
P
M
I
P
S
S
F
S
A
Honey Bee
Apis mellifera
XP_395876
456
51514
R276
P
P
F
T
S
D
N
R
K
K
T
I
E
K
I
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
F326
A
K
L
S
M
P
H
F
L
T
Q
E
A
Q
S
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
Y296
G
K
L
S
L
P
P
Y
L
T
H
E
A
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L284
V
M
L
T
D
F
G
L
A
K
E
F
E
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
40
40
40
N.A.
6.6
0
53.3
80
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
100
66.6
66.6
66.6
N.A.
13.3
6.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
0
0
0
0
0
14
0
7
0
74
0
7
% A
% Cys:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
0
0
0
0
7
0
0
0
47
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
7
74
14
7
0
% E
% Phe:
0
0
7
0
0
7
0
27
0
0
0
7
7
0
0
% F
% Gly:
7
0
0
20
7
0
7
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
0
7
0
0
7
% I
% Lys:
0
74
0
7
0
0
0
0
7
14
0
0
0
7
0
% K
% Leu:
7
0
80
0
47
0
0
7
74
0
7
0
0
0
7
% L
% Met:
0
14
0
0
27
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
40
0
0
14
0
0
0
7
0
0
0
7
% N
% Pro:
7
7
0
0
0
74
54
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
20
0
0
0
47
0
0
27
0
% Q
% Arg:
7
0
7
0
0
0
0
14
0
0
0
0
0
47
0
% R
% Ser:
0
0
0
20
7
0
0
0
0
20
7
7
0
14
20
% S
% Thr:
0
0
0
14
0
0
0
0
0
54
7
0
0
0
0
% T
% Val:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _